Author/treatment type

Follow-up outcomes measures/radiographs

Yu et al. [2] /Bisphosphonates

Mean Enneking limb function score was 26.7 (Range 24 - 29). Radiographic: Lucent zones observed in 4 patients (at average of 8 months) adjacent to the bone cement without progression. All internal fixation was intact without evidence of subchondral bone fracture.

Xu et al. [1] /Bisphosphonates

Independent favorable prognostic factors of overall recurrence free survival (RFS) were age <40 (p < 0.01), total spondylectomy over subtotal (p = 0.04), and bisphosphonate therapy (p = 0.02) Radiographic: Not reported

Tse et al. [4] /Bisphosphonates

Pain scores improved in all patients with average visual analog pain scores decreasing from 7.7 (5 - 8) preoperatively to 3.3 (1 - 4) post-operatively. Also 20 out of 24 patients experienced subjective decrease in swelling. Local recurrence was statistically lower in the bisphosphonate group (p = 0.056). Radiographic: Pre-operative radiographic evidence of mineralization was noted in 14 of 24 patients in the bisphosphonate group.

Cheng et al. [3] /Bisphosphonates

Local recurrence rates were lower in patients treated with pamidronate. Radiographic: Not reported